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SMC2 Polyclonal Antibody
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Product Details
BS-7727R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human SMC2, amino acids 401-500.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
CAP-E and CAP-C (Chromosome Associated Protein-E & C) are also SMC (Structural Maintenance of Chromosome) family members that form a heterodimeric complex required for mitotic chromosome condensation to achieve proper segregation of genetic information during subsequent cell division. hCAP-C/hCAP-E is a component of a multiprotein complex called condensin that interacts with phosphorylation of Histone H3 resulting in the mitotic chromosome condensation. The distribution patterns of the two heterodimeric complexes in interphase nucleus indicate independent behavior of the two complexes during cell cycle. These results suggest that the two distinct complexes are involved in different aspects of mitotic chromosome organization in humar cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CAP E; Chromosome-associated protein E; FGF-inducible protein 16; fibroblast growth factor inducible 16; FLJ10093; hCAP-E; heterodimeric coiled-coil protein required for mitotic chromosome condensation; similar to X. laevis mitotic chromosome condensation protein XCAP-E, encoded by GenBank Accession Number U13674; SMC protein 2; SMC2 (structural maintenance of chromosomes 2, yeast)-like 1; SMC2 protein; SMC2 structural maintenance of chromosomes 2-like 1; structural maintenance of chromosomal proteins; hCAP-E; structural maintenance of chromosomes (SMC) family member; structural maintenance of chromosomes (SMC) family member, chromosome-associated protein E; Structural maintenance of chromosomes protein 2; unnamed protein product; XCAP-E homolog
Gene Aliases: 5730502P04Rik; AI255214; AW545314; CAP-E; CAPE; Fin16; PRO0324; SMC-2; SMC2; SMC2L1
UniProt ID: (Human) O95347, (Mouse) Q8CG48
Entrez Gene ID: (Human) 10592, (Rat) 362519, (Mouse) 14211
mitotic chromosome condensation
meiotic chromosome condensation
meiotic chromosome segregation
kinetochore organization
nuclear division
chromosome condensation
chromosome organization
cell division
positive regulation of chromosome segregation
nuclear chromosome segregation
positive regulation of chromosome separation
positive regulation of chromosome condensation
cell cycle
mitotic nuclear division
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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