The proteins belonging to structural maintenance of chromosomes (SMC) family play critical roles in chromosome structural changes. SMC proteins are involved in the proper condensation and segregation of mitotic chromosomes. Four human SMC proteins that form two distinct heterodimeric complexes in the cell, the human chromosome-associated protein (hCAP)-C and hCAP-E protein complex (hCAP-C/hCAP-E), and the human SMC1 (hSMC1) and hSMC3 protein complex (hSMC1/hSMC3) have been identified.
Protein Aliases: Chromosome-associated polypeptide C; hCAP-C; SMC protein 4; SMC4 structural maintenance of chromosomes 4-like 1; Structural maintenance of chromosomes protein 4; XCAP-C homolog
Gene Aliases: 2500002A22Rik; C79747; CAP-C; CAPC; SMC-4; SMC4; SMC4L1