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Product Details
PA5-51724
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human SMEK1. Recombinant protein control fragment (Product #RP-89035).
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2647633
Product Specific Information
Immunogen sequence: DGEAVVSPSD KTKNDDDIMD PISKFMERKK LKESEEKEVL LKTNLSGRQS PSFKLSLSSG TKTNLTSQSS TTNLPGSPGS PGSPGSPGSP GSVPKNTSQT AAITTKGGLV GLVDYPDDDE DDDEDEDK
Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 97%.
Target Information
Regulatory subunit of serine/threonine-protein phosphatase 4. May regulate the activity of PPP4C at centrosomal microtubule organizing centers. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: protein phosphatase 4, regulatory subunit 3A; Serine/threonine-protein phosphatase 4 regulatory subunit 3A; SMEK homolog 1; SMEK homolog 1, suppressor of mek1
Gene Aliases: FLFL1; KIAA2010; MSTP033; PP4R3; PP4R3A; PPP4R3A; SMEK1; smk-1; smk1
UniProt ID: (Human) Q6IN85
Entrez Gene ID: (Human) 55671
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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