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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • MYH11 Antibodies

          Proteintech

          SMMHC Polyclonal Antibody

          37 References
          View all (43) MYH11 antibodies

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          Cite SMMHC Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (24)
          SMMHC Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          SMMHC Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 24

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          SMMHC Antibody (21404-1-AP) in IHC (P)

          Immunohistochemical analysis of paraffin-embedded Human colon tissue slide using (Product # 21404-1-AP) SMMHC antibody at dilution of 1:2,000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          SMMHC Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SMMHC Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SMMHC Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SMMHC Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SMMHC Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SMMHC Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SMMHC Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SMMHC Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SMMHC Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SMMHC Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SMMHC Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SMMHC Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SMMHC Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SMMHC Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SMMHC Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SMMHC Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SMMHC Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SMMHC Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SMMHC Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SMMHC Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))
          SMMHC Antibody in Western Blot (WB)
          SMMHC Antibody in Western Blot (WB)
          SMMHC Antibody in Western Blot (WB)
          SMMHC Antibody in Flow Cytometry (Flow)

          Product Details

          21404-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:1,000-1:4,000
          View 26 publications 26 publications

          Immunohistochemistry (IHC)

          -
          View 2 publications 2 publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:20-1:200
          -

          Immunohistochemistry (PFA fixed) (IHC (PFA))

          1:50-1:500
          -

          Immunocytochemistry (ICC/IF)

          1:50-1:500
          View 9 publications 9 publications

          Flow Cytometry (Flow)

          Assay-dependent
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Published species

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          SMMHC Fusion Protein Ag16114 (1208-1316 aa encoded by BC104906)

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.17 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          Immunogen sequence: LTEQLEQFK RAKANLDKNK QTLEKENADL AGELRVLGQA KQEVEHKKKK LEAQVQELQS KCSDGERARA ELNDKVHKLQ NEVESVTGML NEAEGKAIKL AKDVASLSSQ (1208-1316 aa encoded by BC104906)

          Target Information

          SM-MHC is a cytoplasmic structural protein, which is a major component of the contractile apparatus in smooth muscle cells. Expression of smooth muscle myosin is developmently regulated, appearing early in smooth muscle development, and is specific for smooth muscle development. Two isoforms of smooth muscle myosin heavy chain have been identified, designated MHC-1 and MHC-2.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: myh11 {ECO:0000312|RGD:3136}; Myosin heavy chain 11; myosin heavy chain 11, smooth muscle; myosin heavy chain 21; Myosin heavy chain, smooth muscle isoform; myosin, heavy chain 11, smooth muscle; myosin, heavy polypeptide 11, smooth muscle; Myosin-11; SMMHC; smooth muscle myosin heavy chain

          View more View less

          Gene Aliases: AAT4; AV071570; FAA4; KIAA0866; MYH11; SM1; SM2; SMHC; SMMHC

          View more View less

          UniProt ID: (Human) P35749

          View more View less

          Entrez Gene ID: (Human) 4629, (Rat) 24582, (Mouse) 17880

          View more View less

          Function(s)
          motor activity protein binding calmodulin binding ATP binding structural constituent of muscle actin filament binding actin binding nucleotide binding
          Process(es)
          smooth muscle contraction metabolic process elastic fiber assembly cardiac muscle fiber development muscle contraction skeletal muscle myosin thick filament assembly mitophagy in response to mitochondrial depolarization
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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