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Proteintech
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Immunogen sequence: QKFSALTFLR VDQDKDKDCS LDCAGSPQKP LCASDGRTFL SRCEFQRAKC KDPQLEIAYR GNCKDVSRCV AERKYTQEQA RKEFQQVFIP ECNDDGTYSQ VQCHSYTGYC WCVTPNGRPI SGTAVAHKTP RCPGSVNEKL PQREGTGKTD DAAAPALETQ PQGDEEDIAS RYPTLWTEQV KSRQNKTNKN SVSSCDQEHQ SALEEAKQP
This gene encodes a member of the SPARC family (secreted protein acidic and rich in cysteine/osteonectin/BM-40), which are highly expressed during embryogenesis and wound healing. The gene product is a matricellular protein which promotes matrix assembly and can stimulate endothelial cell proliferation and migration, as well as angiogenic activity. Associated with pulmonary function, this secretory gene product contains a Kazal domain, two thymoglobulin type-1 domains, and two EF-hand calcium-binding domains. The encoded protein may serve as a target for controlling angiogenesis in tumor growth and myocardial ischemia. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Secreted modular calcium-binding protein 2; SMAP-2; SMOC-2; smooth muscle associated protein 2; Smooth muscle-associated protein 2; SPARC-related modular calcium-binding protein 2; thyroglobulin type-1 repeat containing protein
Gene Aliases: 1700056C05Rik; 5430426J21Rik; bA270C4A.1; bA37D8.1; dJ421D16.1; DTDP1; MST117; MSTP117; MSTP140; SMAP2; SMOC2; Smoc2l
UniProt ID: (Human) Q9H3U7, (Mouse) Q8CD91
Entrez Gene ID: (Human) 64094, (Mouse) 64074
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