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Fabgennix
SMOX Polyclonal Antibody
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Product Details
SMOX-101AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Fruit fly
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide taken within amino acid region 434-484 on D. melanogaster SMOX protein.
Conjugate
Form
Liquid
Concentration
0.5-1.5 mg/mL
Purification
Affinity chromatography
Storage buffer
proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Polyamines are ubiquitous polycationic alkylamines which include spermine, spermidine, putrescine, and agmatine. These molecules participate in a broad range of cellular functions which include cell cycle modulation, scavenging reactive oxygen species, and the control of gene expression. These molecules also play important roles in neurotransmission through their regulation of cell-surface receptor activity, involvement in intracellular signalling pathways, and their putative roles as neurotransmitters. This gene encodes an FAD-containing enzyme that catalyzes the oxidation of spermine to spermadine and secondarily produces hydrogen peroxide. Multiple transcript variants encoding different isoenzymes have been identified for this gene, some of which have failed to demonstrate significant oxidase activity on natural polyamine substrates.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CG2262-PA; CG2262-PB; LD15813p; MAD homolog 2; Mothers against decapentaplegic homolog 2; Protein Smad on X; R-Smad; sisters against dpp; SMAD 2; SMAD family member 2; Smox-PA; Smox-PB; Smox/dSmad2; temporarily deranged
Gene Aliases: CG2262; Dmel\CG2262; Dmel_CG2262; DSMAD2; l(1)G0348; Sad; Smad; SMAD2; Smad2/3; SMOX; ted; tmp
UniProt ID: (Fruit fly) O96660
Entrez Gene ID: (Fruit fly) 31738
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
protein binding
transcription factor binding
chromatin DNA binding
ubiquitin protein ligase binding
I-SMAD binding
DNA-binding transcription factor
gene-specific transcriptional regulator
negative regulation of transcription from RNA polymerase II promoter
positive regulation of neuroblast proliferation
transforming growth factor beta receptor signaling pathway
axon guidance
imaginal disc-derived wing morphogenesis
determination of adult lifespan
anatomical structure morphogenesis
negative regulation of autophagy
mushroom body development
cell differentiation
BMP signaling pathway
activin receptor signaling pathway
glucose homeostasis
regulation of imaginal disc-derived wing size
R8 cell fate specification
positive regulation of imaginal disc growth
positive regulation of transcription from RNA polymerase II promoter
neuron development
dendrite morphogenesis
regulation of synapse structure or activity
SMAD protein signal transduction
cellular response to glucose stimulus
regulation of cell proliferation involved in imaginal disc-derived wing morphogenesis
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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