Immunogen sequence: SPVNSLFVAP AVTPVKSVLE KQTNNPGIRL FQYDPRDYKL LDMLQYYLNL TEANLKGESI WKLEYILTQT YDIEDLQPES LYGLAKQFTI LDSKQFIKYY NYFFVSYDSS ATCDKTCKAF QICAIM
Highest antigen sequence identity to the following orthologs: Mouse - 74%, Rat - 76%.
Has in vitro nucleotide phosphodiesterase activity with nucleoside triphosphates, such as ATP (PubMed:25288789, PubMed:26783088). Has in vitro activity with p-nitrophenyl-TMP (PubMed:25288789). Has lower activity with nucleoside diphosphates, and no activity with nucleoside monophosphates (PubMed:25288789, PubMed:26783088). Has in vitro activity with CDP-choline, giving rise to CMP and phosphocholine. Has in vitro activity with CDP-ethanolamine (PubMed:26783088). Does not have sphingomyelin phosphodiesterase activity (PubMed:25288789, PubMed:26783088). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 0610010C24Rik; Acid sphingomyelinase-like phosphodiesterase 3a; ASM-like phosphodiesterase 3a; sphingomyelin phosphodiesterase acid-like 3A; sphingomyelin phosphodiesterase, acid-like 3A
Gene Aliases: ASM3A; ASML3A; SMPDL3A; yR36GH4.1
UniProt ID: (Human) Q92484
Entrez Gene ID: (Human) 10924