Covalent modification of target lysines by SUMO (small ubiquitin-like modifier) modulates processes such as protein localization, transcription, nuclear transport, mitosis, DNA replication and repair, signal transduction, and viral reproduction. SUMO does not seem to be involved in protein degradation and may in fact function as an antagonist of ubiquitin in the degradation process. In the development of Drosophila, SUMO plays a maternal role in anterior-posterior (A/P) polarity and patterning.
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Protein Aliases: CG4494-PA; CG4494-PB; LD07775p; lethal (2) SH0182; small Ubiquitin-like modifier; smt3; smt3-PA; smt3-PB; SUMO; SUMO protein
Gene Aliases: anon-EST:Posey240; CG4494; Dm0342; Dmel\CG4494; Dmel_CG4494; DmSmt3; DmSUMO-1; dSmt3; l(2)04493; l(2)SH0182; l(2)SH2 0182; SMT3; SUMO
Entrez Gene ID: (Fruit fly) 33981