Keep as concentrated solution.
Positive Control: HeLa, Hela (1 ng/ml TGF-beta and 300 ng/ml of EGF for 2 hr), HeLa (starvation for 16 hr, 20 ng/ml TGF-beta and 300 ng/ml EGF treatment for 30 min).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
Zinc finger protein SNAI1 (SNAIL)is a zinc finger transcriptional repressor which down regulates the expression of the ectodermal gene within the mesoderm and functions to form the mesoderm and neural crest. It is reported that SNAI1 acts as an important factor of tumor invasion as evidenced by its role in E-cadherin down-regulation and induction of epithelial-mesenchymal transition (EMT). In human breast cancer, the expression of SNAI1 and/or the homologous SNAI2 (Slug) has been associated with E-cadherin repression, local or distant metastasis, tumor recurrence, or poor prognosis in different tumor series. It is also reported that Snail 1 protein in the stromamay be anew putative prognosis marker for colon tumors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: dJ710H13.1 Antibody; Protein sna; Protein snail homolog 1; SLUGH2 Antibody; SNA Antibody; SNAH Antibody; snail 1 homolog; snail 1 zinc finger protein; snail 1, zinc finger protein; SNAIL Antibody; snail family zinc finger 1; snail homolog 1; snail homolog 1 (Drosophila) Antibody; SNAIL1 Antibody; Zinc finger protein SNAI1
Gene Aliases: AI194338; dJ710H13.1; SLUGH2; SNA; Sna1; SNAH; SNAI1; SNAIL; SNAIL1