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          • Primary Antibodies ›
          • SNAP23 Antibodies

          Osenses

          SNAP23 Polyclonal Antibody

          5 References
          View all (13) SNAP23 antibodies

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          Cite SNAP23 Polyclonal Antibody

          Additional Information:
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          SNAP23 Polyclonal Antibody

          Product Details

          OSS00166W-100UL

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:300-1:2,000
          -

          Immunohistochemistry (IHC)

          1:300-1:2,000
          -

          Miscellaneous PubMed (Misc)

          -
          View 5 publications 5 publications
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / Ig

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          A synthetic peptide from c-terminal region of human Synaptosomal-associated protein 23 (SNAP23) conjugated to an immunogenic carrier protein was used as the antigen
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Lyophilized

          Concentration

          Conc. Not Determined

          Storage buffer

          whole serum

          Contains

          no preservative

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Product Specific Information

          Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.

          Specificity of this antibody: SNAP-23.

          Target Information

          Specificity of vesicular transport is regulated, in part, by the interaction of a vesicle-associated membrane protein termed synaptobrevin/VAMP with a target compartment membrane protein termed syntaxin. These proteins, together with SNAP25 (synaptosome-associated protein of 25 kDa), form a complex which serves as a binding site for the general membrane fusion machinery. Synaptobrevin/VAMP and syntaxin are believed to be involved in vesicular transport in most, if not all cells, while SNAP25 is present almost exclusively in the brain, suggesting that a ubiquitously expressed homolog of SNAP25 exists to facilitate transport vesicle/target membrane fusion in other tissues. The protein encoded by this gene is structurally and functionally similar to SNAP25 and binds tightly to multiple syntaxins and synaptobrevins/VAMPs. It is an essential component of the high affinity receptor for the general membrane fusion machinery and is an important regulator of transport vesicle docking and fusion. Two alternative transcript variants encoding different protein isoforms have been described for this gene.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: OTTHUMP00000161263; SNAP-23; SNAP23; Synaptosomal-associated protein 23; synaptosomal-associated protein, 23kD; synaptosomal-associated protein, 23kDa; synaptosome associated protein 23kDa; unnamed protein product; Vesicle-membrane fusion protein SNAP-23

          View more View less

          Gene Aliases: HsT17016; SNAP-23; SNAP23; SNAP23A; SNAP23B

          View more View less

          UniProt ID: (Human) O00161

          View more View less

          Entrez Gene ID: (Human) 8773

          View more View less

          Function(s)
          SNAP receptor activity protein binding syntaxin binding
          Process(es)
          histamine secretion by mast cell exocytosis post-Golgi vesicle-mediated transport vesicle targeting protein transport synaptic vesicle priming synaptic vesicle fusion to presynaptic active zone membrane membrane fusion
          It has to be done as per old AB suggested Products section.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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