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Proteintech
SNCB Polyclonal Antibody
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Product Details
10498-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SNCB Fusion Protein Ag0772 (1-134 aa encoded by BC002902)
Conjugate
Form
Liquid
Concentration
0.15 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MDVFMKGLS MAKEGVVAAA EKTKQGVTEA AEKTKEGVLY VGSKTREGVV QGVASVAEKT KEQASHLGGA VFSGAGNIAA ATGLVKREEF PTDLKPEEVA QEAAEEPLIE PLMEPEGESY EDPPQEEYQE YEPEA (1-134 aa encoded by BC002902)
Target Information
Synuclein family of proteins is abundantly expressed in neuronal cytosol and presynaptic terminals. In vertebrates they are encoded by three different genes. Synucleins have been specifically implemented in three major diseases: Alzheimer's (AD), Parkinson's PD) and breast cancer. In AD, a peptide derived from alpha synuclein forms an intrinsic component of plaque amyloid. In PD, an alpha synuclein accumulates in Lewy bodies. An allele of alpha synuclein has been linked to many familial cases of PD. In breast cancer increased expression of gamma synuclein correlates with the disease progression. Synucleins appear to be involved in the membrane plasticity in developing song control system of songbirds.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Beta-synuclein; Phosphoneuroprotein 14; PNP 14
Gene Aliases: AI838531; betaSYN; SNCB
UniProt ID: (Human) Q16143, (Mouse) Q91ZZ3, (Rat) Q63754
Entrez Gene ID: (Human) 6620, (Mouse) 104069, (Rat) 113893
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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