Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Invitrogen
This Antibody was verified by Knockout to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 9
Immunogen sequence: MVLSGCAIIV RGQPRGGPPP ERQINLSNIR AGNLARRAAA TQPDAKDTPD EPWAFPAREF LRKKLIGKEV CFTIENKTPQ GREYGMIYLG KDTNGENIAE SLVAEGLATR REGMRANNPE QNRLSECEEQ AKAAKKGMWS EGNGSHTIRD LKYTIENPRH FVDSHHQKPV NAIIEHVRDG SVVRALLLPD YYLVTVMLSG IKCPTFRREA DGSETPEPFA AEAKFFTESR LLQRDVQIIL ESCHNQNILG TILHPNGNIT; Positive Samples: HeLa, Jurkat, HL-60, MCF7, 293T, Mouse liver, Rat liver; Cellular Location: Cytoplasm, Melanosome, Nucleus
SND1/P100 (staphylococcal nuclease and tudor domain containing 1), also known as TudorSN, functions in the Pim-1 regulation of Myb activity and acts as a transcriptional activator of EBNA-2. It also interacts with EAV, NSP1, GTF2E1 and GTF2E2, and forms a ternary complex with Stat6 and POLR2A. The staphylococcal nuclease-like (SN)-domains directly interact with amino acids 1099-1758 of CBP. SND1/P100 plays an important role in the assembly of Stat6 transcriptome and stimulates IL-4-dependent transcription by mediating interaction between Stat6 and CBP.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 100 kDa coactivator; EBNA-2 co-activator (100kD); EBNA2 coactivator p100; p100 co-activator; p100 EBNA2 co-activator; p105 coactivator; SND p102; SND1-BRAF fusion; staphylococcal nuclease domain containing 1; Staphylococcal nuclease domain-containing protein 1; testis tissue sperm-binding protein Li 82P; Tudor domain-containing protein 11; Tudor-SN; TudorSN
Gene Aliases: AL033314; p100; SND p102; SND1; TDRD11; Tudor-SN
UniProt ID: (Human) Q7KZF4, (Rat) Q66X93, (Mouse) Q78PY7
Entrez Gene ID: (Human) 27044, (Rat) 64635, (Mouse) 56463
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