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Invitrogen
SNRNP200 Polyclonal Antibody
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FIGURE: 1 / 1
SNRNP200 Antibody (PA5-110405) in WB
Western blot analysis of SNRNP200 in extracts of various cell lines. Samples were incubated with SNRNP200 Polyclonal antibody (Product # PA5-110405) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Product Details
PA5-110405
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1947-2136 of human SNRNP200 (NP_054733.2).
Conjugate
Form
Liquid
Concentration
3.19 mg/mL
Amount
319 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: QMVTQAMWSK DSYLKQLPHF TSEHIKRCTD KGVESVFDIM EMEDEERNAL LQLTDSQIAD VARFCNRYPN IELSYEVVDK DSIRSGGPVV VLVQLEREEE VTGPVIAPLF PQKREEGWWV VIGDAKSNSL ISIKRLTLQQ KAKVKLDFVA PATGAHNYTL YFMSDAYMGC DQEYKFSVDV KEAETDSDSD
Target Information
Pre-mRNA splicing is catalyzed by the spliceosome, a complex of specialized RNA and protein subunits that removes introns from a transcribed pre-mRNA segment. The spliceosome consists of small nuclear RNA proteins (snRNPs) U1, U2, U4, U5 and U6, together with approximately 80 conserved proteins. U5 snRNP contains nine specific proteins. This gene encodes one of the U5 snRNP-specific proteins. This protein belongs to the DEXH-box family of putative RNA helicases. It is a core component of U4/U6-U5 snRNPs and appears to catalyze an ATP-dependent unwinding of U4/U6 RNA duplices. Mutations in this gene cause autosomal-dominant retinitis pigmentosa. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Activating signal cointegrator 1 complex subunit 3-like 1; bad response to refrigeration 2 homolog; BRR2 homolog; contains two DEXH helicase domains; hBRR2/200K protein; U5-200K; small nuclear ribonucleoprotein 200kDa (U5); small nuclear ribonucleoprotein, U5 200kDa subunit; U5 small nuclear ribonucleoprotein 200 kDa helicase; U5 snRNP-specific 200 kDa protein; U5-200KD; unnamed protein product
Gene Aliases: ASCC3L1; BRR2; HELIC2; KIAA0788; RP33; SNRNP200; U5-200KD
UniProt ID: (Human) O75643
Entrez Gene ID: (Human) 23020
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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