Peptide sequence: MPGQMPPAQP LSENPPNHIL FLTNLPEETN ELMLSMLFNQ FPGFKEVRLV
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 85%
The protein encoded by this gene associates with stem loop II of the U1 small nuclear ribonucleoprotein, which binds the 5 and apos; splice site of precursor mRNAs and is required for splicing. The encoded protein autoregulates itself by polyadenylation inhibition of its own pre-mRNA via dimerization and has been implicated in the coupling of splicing and polyadenylation.
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Protein Aliases: Mud1; nuclear ribonucleoprotein A; protein A of the U1 small nuclear RNA; Small nuclear ribonucleoprotein polypeptide A; U1 small nuclear ribonucleoprotein A; U1 small nuclear RNP-specific A; U1 snRNP A; U1 snRNP protein A; U1 snRNP-specific protein A; U1-A; U1A
Gene Aliases: BOS_17511; C430021M15Rik; fc19d01; Mud1; Rnu1a-1; Rnu1a1; SNRPA; U1-A; U1A; wu:fc19d01; zgc:77810