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Immunogen sequence: IIAKMKGTFV ERDRKREKRK PKSQETPATK KAVQGGGATP VVGAVQGPVP GMPPMTQAPR IMHHMPGQPP YMP
Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 95%.
The protein encoded by this gene associates with stem loop II of the U1 small nuclear ribonucleoprotein, which binds the 5' splice site of precursor mRNAs and is required for splicing. The encoded protein autoregulates itself by polyadenylation inhibition of its own pre-mRNA via dimerization and has been implicated in the coupling of splicing and polyadenylation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: U1 small nuclear ribonucleoprotein A; U1 small nuclear RNP-specific A; U1 snRNP A; U1 snRNP-specific protein A
Gene Aliases: Mud1; SNRPA; U1-A; U1A
UniProt ID: (Human) P09012
Entrez Gene ID: (Human) 6626
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