This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
Immunogen sequence: QAPAGLAGPV RGVGGPSQQV MTPQGRGT
The protein encoded by this gene is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs). These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding different isoforms (B and B') have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: B polypeptide of Sm protein; Sm protein B/B'; Sm-B/B'; sm-B/Sm-B'; small nuclear ribonucleoprotein polypeptide B; small nuclear ribonucleoprotein polypeptides B and B'; Small nuclear ribonucleoprotein-associated proteins B and B'; snRNP-B
Gene Aliases: CCMS; COD; Sm-B/B'; SmB/B'; SmB/SmB'; snRNP-B; SNRPB; SNRPB1
UniProt ID: (Human) P14678
Entrez Gene ID: (Human) 6628
Molecular Function: RNA splicing factor