|Tested species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide made to an internal portion of the human protein (within residues 150-200).|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS with 30% glycerol|
|Contains||0.1% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100|
|Western Blot (WB)||0.5 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
The target sequence has 94% sequence homology with rat and bovine.
SNX27 is a member of the sorting nexin family of proteins that is involved in endocytic trafficking. In T lymphocytes, SNX27 participates in the endocytic recycling pathway. It has also been shown that the single PDZ domain of SNX27 binds directly to the PDZ binding motif of Kir3 channels, which leads to their downregulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.