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Immunogen sequence: MATKARVMY DFAAEPGNNE LTVNEGEIIT ITNPDVGGGW LEGRNIKGER GLVPTDYVEI LPSDGKDQFS CGNSVADQAF LDSLSASTAH ASSSAASNNH QVGSGNDPWS AWSASKSGNW ESSEGWGAQP EGAGAQRNTN TPNNWDTAFG HPQAYQGPAT GDDDDWDEDW DGPKSSSYFK DSESADAGGA QRGNSRASSS SMKIPLNKFP GFAKPGTEQY LLAKQLAKPK EKIPIIVGDY GPMWVYPTST FDCVVADPRK GSKMYGLKSY IEYQLTPTNT NRSVNHRYKH FDWLYERLLV KFGSAIPIPS LPDKQVTGRF EEEFIKMRME RLQAWMTRMC RHPVISESEV FQQFLNFRDE KEW (1-362 aa encoded by BC005022)
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members, but does contain a SH3 domain near its N-terminus. This protein interacts with the cytoplasmic domains of the precursor but not the processed forms of a disintegrin and metalloprotease domain 9 and 15. This protein binds the beta-appendage domain of adaptor protein 2 and may function to assist adaptor protein 2 in its role at the plasma membrane. This protein interacts with activated Cdc42-associated kinase-2 to regulate the degradation of epidermal growth factor receptor protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: MST155; MSTP155; OTTHUMP00000040083; Protein SDP1; RP11-266C7.10; SH3 and PX domain-containing protein 1; SH3 and PX domain-containing protein 3A; Sorting nexin-9; Wiskott-Aldrich syndrome protein (WASP) interactor protein
Gene Aliases: 2700073N08Rik; SDP1; SH3PX1; SH3PXD3A; SNX9; WISP
UniProt ID: (Human) Q9Y5X1, (Mouse) Q91VH2
Entrez Gene ID: (Human) 51429, (Mouse) 66616, (Rat) 683687
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