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Western blot analysis of HepG2 Whole Cell Lysate using PA5-19813, SOCS2 primary antibody at a dilution of 1 ug/ml (lane 1). PA5-19813 staining of Mouse Thymus Tissue Lysate at a dilution of 1 ug/ml (lane 2). Blot treated with a secondary HRP-conjugated Goat polyclonal anti-Rabbit antibody was used at a dilution of 1:3000.
|Tested species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide conjugated to KLH derived from within residues 150 to the C-terminus of Human SOCS2 .|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.4, with 1% BSA|
|Contains||0.02% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This antibody is predicted to react with rat, cow, pig and chimpanzee based on sequence homology.
This gene encodes a member of the STAT-induced STAT inhibitor , also known as suppressor of cytokine signaling , family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10 and interferon -gamma. The protein encoded by this gene is found to interact with the cytoplasmic domain of insulin-like growth factor-1 receptor , and thus is thought to be involved in the regulation of IGF1R mediated cell signaling. Knockout studies in mice also suggested a regulatory role of this gene in IGF-1 related growth control.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
CIS-2; CIS2, Cish2, SOCS-2, SSI-2, SSI2, STATI2, CIS-2; cytokine inducible SH2-containing protein 2; cytokine-inducible SH2 protein 2; STAT induced STAT inhibitor-2; STAT-induced STAT inhibitor 2; STAT-induced STAT inhibitor-2; suppressor of cytokine signaling 2; suppressor of cytokine signaling-2
8030460M17; AI527257; AW108012; CIS2; Cish2; D130043N08Rik; hg; JAB; SOCS-2; SOCS2; SSI-2; SSI2; STATI2