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Proteintech
SOCS4 Polyclonal Antibody
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Product Details
27191-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SOCS4 fusion protein Ag25887
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: MAENNENISK NVDVRPKTSR SRSADRKDGY VWSGKKLSWS KKSESYSDAE TVNGIEKTEV SLRNQERKHS CSSIELDLDH SCGHRFLGRS LKQKLQDAVG QCFPIKNCSS RHSSGLPS
Target Information
The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS), also known as STAT-induced STAT inhibitor (SSI), protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: SH2 domain containing SOCS box protein; SOCS-4; SOCS-7; Suppressor of cytokine signaling 4; Suppressor of cytokine signaling 7; suppressor of cytokine signalling 4
Gene Aliases: 3110032M18Rik; A730004F22Rik; AI427843; AU015727; AU015859; SOCS4; SOCS7
UniProt ID: (Human) Q8WXH5, (Mouse) Q91ZA6
Entrez Gene ID: (Human) 122809, (Mouse) 67296
negative regulation of epidermal growth factor-activated receptor activity
protein ubiquitination
cytokine-mediated signaling pathway
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
intracellular signal transduction
regulation of growth
negative regulation of JAK-STAT cascade
negative regulation of protein kinase activity
negative regulation of signal transduction
negative regulation of epidermal growth factor receptor signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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