|Tested species reactivity||Bovine, Dog, Hamster, Human, Mouse, Non-human primate, Sheep, Pig, Rabbit, Rat, Xenopus|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Full length protein (Human).|
|Storage buffer||0.05M sodium phosphate, pH 7.2, with 0.1% BSA, 50% glycerol|
|Contains||0.1% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay Dependent|
|Immunohistochemistry (IHC)||1 µg/ml|
|Immunoprecipitation (IP)||10 µg/ml|
|Western Blot (WB)||1:5000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-31072 detects MnSOD from hamster, Xenopus laevis, canine, rat, human, mouse, bovine, ovine, porcine, rabbit, and monkey samples.
PA1-31072 has been successfully used in immunohistochemistry, immunoprecipitation, Western blot, and ELISA applications.
The PA1-31072 immunogen is full length protein (Human).
Rat brain tissue extract was used as a positive control.
This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.