Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: SOD3.
This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This gene, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ALS1; EC SOD; EC-SOD; Extracellular superoxide dismutase [Cu-Zn]; MGC20077; SOD 3; superoxide dismutase; testicular tissue protein Li 175
Gene Aliases: EC-SOD; SOD3
UniProt ID: (Human) P08294
Entrez Gene ID: (Human) 6649
Molecular Function: oxidoreductase