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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • SOX3 Antibodies

          AbboMax

          SOX-3 Polyclonal Antibody

          View all (9) SOX3 antibodies

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          Cite SOX-3 Polyclonal Antibody

          • Antibody Testing Data (1)
          SOX-3 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.
          SOX-3 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          SOX-3 Antibody (601-500) in WB

          Western Blot: The whole cell lysate derived from neuron stem cell (NE-4C) (20 µg/lane) was immunoblotted by Rabbit anti-SOX-3 (Cat#601-500) at 1:500. An immunoreactive protein band was observed around 46 kDa. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          SOX-3 Antibody in Western Blot (WB)
          SOX-3 Polyclonal Antibody

          Product Details

          601-500

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          0.1-1 µg/mL
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          2-10 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          A synthetic peptide derived from N-terminus of Human SOX-3 protein
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.5 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS with proprietary stabilizer

          Contains

          0.01% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Product Specific Information

          Positive control: Brain tissue

          Cellular location: Nuclear.

          Target Information

          This gene encodes a member of the SOX family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. Mutations in this gene have been associated with X-linked mental retardation with growth hormone deficiency.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: SRY (sex determining region Y)-box 3; SRY box 3; Transcription factor SOX-3

          View more View less

          Gene Aliases: GHDX; MRGH; PHP; PHPX; SOX3; SOXB

          View more View less

          UniProt ID: (Human) P41225

          View more View less

          Entrez Gene ID: (Human) 6658

          View more View less

          Function(s)
          RNA polymerase II core promoter sequence-specific DNA binding RNA polymerase II transcription corepressor activity DNA binding transcription factor activity, sequence-specific DNA binding HMG box transcription factor
          Process(es)
          negative regulation of transcription from RNA polymerase II promoter transcription, DNA-templated central nervous system development sensory organ development sex determination hypothalamus development pituitary gland development negative regulation of neuron differentiation neuron development face development
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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