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Product Details
PA5-30599
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Full length human SOX6 Recombinant protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 1% BSA, 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2548073
Product Specific Information
Recommended positive controls: U87-MG.
Predicted reactivity: Mouse (96%), Rat (91%), Chicken (89%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Transcriptional activator. Binds specifically to the DNA sequence 5'-AACAAT-3'. Plays a key role in several developmental processes, including neurogenesis and skeleton formation.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: SRY (sex determining region Y)-box 6; SRY box 6; SRY-box containing gene 6; Transcription factor SOX-6
Gene Aliases: HSSOX6; SOX6; SOXD
UniProt ID: (Human) P35712
Entrez Gene ID: (Human) 55553
negative regulation of transcription from RNA polymerase II promoter
cell morphogenesis
in utero embryonic development
transcription, DNA-templated
regulation of transcription, DNA-templated
muscle organ development
post-embryonic development
gene silencing
oligodendrocyte cell fate specification
positive regulation of chondrocyte differentiation
positive regulation of transcription from RNA polymerase II promoter
astrocyte differentiation
erythrocyte development
cartilage development
cardiac muscle cell differentiation
positive regulation of cartilage development
cellular response to transforming growth factor beta stimulus
negative regulation of cardiac muscle cell differentiation
positive regulation of mesenchymal stem cell differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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