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Invitrogen
SOX7 Polyclonal Antibody
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FIGURE: 1 / 1
SOX7 Antibody (PA5-80055) in WB
Western blot analysis of SOX7 in Lane 1: rat brain tissue lysate, Lane 2: human placenta tissue lysate, Lane 3: rat lung tissue lysate, Lane 4: rat testis tissue lysate, Lane 5: HeLa whole cell lysate, Lane 6: A549 whole cell lysate, Lane 7: HEPG2 whole cell lysate, Lane 8: SMMC whole cell lysate, Lane 9: NEURO whole cell lysate using 40-50 µg per well. Sample was incubated with SOX7 (Product # PA5-80055) at a dilution of 0.5 µg/mL.
Product Details
PA5-80055
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human SOX7 (370-388aa LISVLADATATYYNSYSVS).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5mg BSA
Contains
0.05mg sodium azide, 0.05mg thimerosal
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: Rat Brain Tissue, Human Placenta Tissue, Rat Lung Tissue, Rat Testis Tissue, HELA whole cell, A549 whole cell, HEPG2 whole cell, SMMC whole cell, NEURO whole cell.
Target Information
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may play a role in tumorigenesis. A similar protein in mice is involved in the regulation of the wingless-type MMTV integration site family (Wnt) pathway.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MGC10895; mSOX7; SRY (sex determining region Y)-box 7; SRY-box 7; SRY-box containing gene 7; Transcription factor SOX-7; unnamed protein product
Gene Aliases: Sox-7; SOX7
UniProt ID: (Human) Q9BT81, (Mouse) P40646
Entrez Gene ID: (Human) 83595, (Mouse) 20680, (Rat) 290317
transcription regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
sequence-specific DNA binding
sequence-specific double-stranded DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
transcription regulatory region DNA binding
molecular_function
HMG box transcription factor
endoderm formation
regulation of transcription from RNA polymerase II promoter
tissue development
cell differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
anatomical structure formation involved in morphogenesis
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
negative regulation of cell proliferation
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
regulation of canonical Wnt signaling pathway
biological_process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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