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|Tested species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||synthetic peptide GDGHHHGDHTGQTHG conjugated to BSA, corresponding to amino acids 209-223 of Human SOX8.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.2, with 50% glycerol|
|Contains||0.09% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunoprecipitation (IP)||Assay dependent|
|Western Blot (WB)||1:200-1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-28072 detects SOX8 from human and mouse samples.
PA1-28072 has been successfully used in immunohistochemistry, immunoprecipitation, and Western blot applications.
The PA1-28072 immunogen is synthetic peptide: GDGHHHGDHTGQTHG conjugated to BSA, corresponding to amino acids 209-223 of Human SOX8.
Store at 4°C short term. For extended storage aliquot and store at -20°C, avoiding freeze/thaw cycles.
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein may be involved in brain development and function. Haploinsufficiency for this protein may contribute to the mental retardation found in haemoglobin H-related mental retardation (ART-16 syndrome).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
MGC24837; SRY (sex determining region Y)-box 8; SRY box 8; SRY-box containing gene 8; Transcription factor SOX-8