This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
Immunogen sequence: QARTHHNQAS DIIVISSEDS EGSTDVDEPL EVFISAPRSE PVINNDNPLE SNDEKEGQEA TCSRPQIVPE PMDFRKLSTF RESFKKRVIG QDHDFSESSE
Highest antigen sequence identity to the following orthologs: Mouse - 24%, Rat - 26%.
This gene encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia)-SP100 nuclear bodies. PML and SP100 are covalently modified by the SUMO-1 modifier, which is considered crucial to nuclear body interactions. The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis, immunity, and gene regulation. Alternatively spliced variants have been identified for this gene; one of which encodes a high-mobility group protein. [provided by RefSeq, Aug 2011].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DKFZp686E07254; FLJ00340; FLJ34579; Lysp100b; nuclear antigen Sp100; Nuclear autoantigen Sp-100; Nuclear dot-associated Sp100 protein; SP100-HMG nuclear autoantigen; Speckled 100 kDa
Gene Aliases: lysp100b; SP100
UniProt ID: (Human) P23497
Entrez Gene ID: (Human) 6672