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Fabgennix
SPACA3 Polyclonal Antibody
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Product Details
SPACA3-301AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptides taken within amino acid region 20-70 on human sperm acrosome membrane-associated protein 3 isoform 2.
Conjugate
Form
Liquid
Concentration
0.5-1.5 mg/mL
Purification
Affinity chromatography
Storage buffer
proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
SPACA3 (sperm acrosome associated 3), also known as sperm lysozyme-like protein 1, lysozyme-like protein 3, lysozyme-like acrosomal sperm-specific secretory protein ALLP-17, cancer/testis antigen 54 (CT54), LYC3, SPRASA or LYZL3, is a 215 amino acid protein that participates in the fusion and adhesion of sperm and egg plasma membrane during fertilization. Identified as a novel cancer/testis antigen in hematologic malignancies, SPACA3 has the ability to elicit B-cell immune responses in patients with cancer and is considered a potential target for immunotherapy. A member of the glycosyl hydrolase 22 family which is expressed in testis, placenta and epididymis, SPACA3 exists as two alternatively spliced isoforms; SPACA3 isoform 1 is a single-pass type II membrane protein of the sperm acrosome whereas SPACA3 isoform 2 is a secreted protein. Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. It could be a potential receptor for the egg oligosaccharide residue N-acetylglucosamine, which is present in the extracellular matrix over the egg plasma membrane. The processed form has no detectable bacteriolytic activity in vitro.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: acrosomal sperm protein; Cancer/testis antigen 54; CT54; lysozyme C; Lysozyme-like acrosomal sperm-specific secretory protein ALLP-17; Lysozyme-like protein 3; lysozyme-like sperm-specific secretory protein ALLP17; mSLLP1; Sperm acrosome membrane-associated protein 3; sperm c-type lysozyme-like protein; Sperm lysozyme-like protein 1; sperm lysozyme-like protein 1 precusor; sperm lyzozyme-like acrosomal protein 1; Sperm protein reactive with antisperm antibodies; Sperm protein reactive with ASA
Gene Aliases: 1700025M08Rik; ALLP17; CT54; LYC3; LYZC; LYZL3; mSLLP1; SLLP1; SPACA3; SPRASA; UNQ424/PRO862
UniProt ID: (Human) Q8IXA5, (Mouse) Q9D9X8
Entrez Gene ID: (Human) 124912, (Mouse) 75622, (Rat) 287557
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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