Immunogen sequence: DSLGREAKCY NELNGCTKIY DPVCGTDGNT YPNECVLCFE NRKRQTSILI QKSGPC; Positive Samples: Mouse intestine
The protein encoded by this gene is a trypsin inhibitor, which is secreted from pancreatic acinar cells into pancreatic juice. It is thought to function in the prevention of trypsin-catalyzed premature activation of zymogens within the pancreas and the pancreatic duct. Mutations in this gene are associated with hereditary pancreatitis and tropical calcific pancreatitis. [provided by RefSeq].
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Protein Aliases: P12; Pancreatic secretory trypsin inhibitor; Prostatic secretory glycoprotein; serine peptidase inhibitor, Kazal type 3; Serine protease inhibitor Kazal-type 1; Serine protease inhibitor Kazal-type 3; serine protease inhibitor, Kazal type 1; serine protease inhibitor, Kazal type 3; TATI; Tumor-associated trypsin inhibitor
Gene Aliases: p12; PCTT; PSTI; SPINK1; Spink3; TATI; TCP