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Invitrogen
SPINK5 Polyclonal Antibody
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Product Details
PA5-52645
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human SPINK5
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
Product Specific Information
Immunogen sequence: DGRLGCTREN DPVLGPDGKT HGNKCAMCAE LFLKEAENAK REGETRIRRN AEKDFCKEYE KQVRNGRLFC TRESDPVRGP DGRMHGNKCA LCAEIFKQRF SEENSKTDQN
Highest antigen sequence identity to the following orthologs: Mouse - 77%, Rat - 74%.
Target Information
Lympho-epithelial Kazal-type inhibitor (LEKTI) is a serine protease inhibitor which protects mucous epithelia against microbial attack and inflammation. LEKTI is a marker of epithelial differentiation and expresses strongly in the granular and uppermost spinous layers of the epidermis and differentiated layers of stratified epithelia. Defects in SPINK5, the gene encoding LEKTI, are the cause of Netherton syndrome, a severe autosomal recessive disorder characterized by atopic dermatitis, hayfever and other conditions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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