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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • SPINK7 Antibodies

          Bioss

          SPINK7 Polyclonal Antibody

          View all (7) SPINK7 antibodies

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          Cite SPINK7 Polyclonal Antibody

          • Antibody Testing Data (1)
          SPINK7 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          SPINK7 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          SPINK7 Antibody (BS-0500R) in IHC (P)

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          SPINK7 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SPINK7 Polyclonal Antibody

          Product Details

          BS-0500R

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:300-1:1,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:200-1:400
          -

          Immunohistochemistry (Frozen) (IHC (F))

          1:100-1:500
          -

          Immunocytochemistry (ICC/IF)

          1:50-1:200
          -

          ELISA (ELISA)

          1:500-1:1,000
          -
          Product Specifications

          Species Reactivity

          Human, Mouse

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          KLH conjugated synthetic peptide derived from human SPINK7, amino acids 51-85.
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Protein A

          Storage buffer

          0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA

          Contains

          0.02% ProClin 300

          Storage conditions

          -20°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Target Information

          SPINK7 (serine peptidase inhibitor, Kazal type 7), also known as Ecg2 (esophagus cancer-related gene 2 protein), is a 76 amino acid secreted protein. Containing one Kazal-like domain, SPINK7 is thought to be a serine protease inhibitor. The gene that encodes SPINK7 maps to human chromosome 5, which contains 181 million base pairs encoding around 1,000 genes. Chromosome 5 is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.Probable serine protease inhibitor.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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          Cite this product

          Bioinformatics

          Protein Aliases: ECRG-2; esophagus cancer related gene 2; Esophagus cancer-related gene 2 protein; esophagus cancer-related gene-2; Serine protease inhibitor Kazal-type 7

          View more View less

          Gene Aliases: ECG2; ECRG2; EG408198; SPINK7; UNQ745/PRO1474

          View more View less

          UniProt ID: (Human) P58062, (Mouse) Q6IE32

          View more View less

          Entrez Gene ID: (Human) 84651, (Mouse) 408198

          View more View less

          Function(s)
          serine-type endopeptidase inhibitor activity protein binding molecular_function peptidase inhibitor activity protease inhibitor
          Process(es)
          negative regulation of serine-type endopeptidase activity biological_process negative regulation of peptidase activity
          It has to be done as per old AB suggested Products section.
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