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Invitrogen
SPINLW1 Polyclonal Antibody
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Product Details
PA5-50656
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to a region derived from internal residues of human epididymal peptidase inhibitor
Conjugate
Form
Liquid
Concentration
2.4 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 40% glycerol
Contains
0.05% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
The antibody detects endogenous levels of total EPPIN protein.
Target Information
Eppin, an epididymal protease inhibitor, belongs to the WFDC family and to the telomeric cluster. The gene encoding the protein is localized to chromosome 20q12-q13 in centromeric and telomeric clusters. It expresses three mRNAs encoding two isoforms of a cystine-rich protein that contains Kunitz-type and WAP-type (four disulfide core) protease inhibitor consensus sequences. The mouse gene lies in a cluster of putative Eppin-like genes on mouse chromosome 2. Following ejaculation, Eppin is bound to semenogelin in seminal plasma and on human spermatozoa. This complex of Eppin and Semenogelin can provide antimicrobial activity for spermatozoa. It can also provide for the preparation and survival of spermatozoa for fertility in the female reproductive tract. Eppin, which is a secreted protein, is expressed in epididymis and testis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cancer/testis antigen 71; cancer/testis antigen 72; CT71; Epididymal protease inhibitor; Eppin; EPPIN1; EPPIN2; EPPIN3; Protease inhibitor WAP7; serine peptidase inhibitor-like, with Kunitz and WAP domains 1 (eppin); Serine protease inhibitor-like with Kunitz and WAP domains 1; serine protease inhibitor-like, with Kunitz and WAP domains 1 (eppin); WAP four-disulfide core domain protein 7
Gene Aliases: 1700024E17Rik; CT71; CT72; dJ461P17.2; EPPIN; SPINLW1; WAP7; WFDC7
UniProt ID: (Human) O95925, (Mouse) Q9DA01
Entrez Gene ID: (Human) 57119, (Mouse) 75526
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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