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OriGene
SPINT1 Monoclonal Antibody (OTI4H2), TrueMAB™
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Product Details
CF504591
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Dog,
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI4H2
Immunogen
Full length human recombinant protein of human SPINT1 produced in HEK293T cell.
Conjugate
Form
Lyophilized
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 8% trehalose
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
Target Information
The protein encoded by this gene is a member of the Kunitz family of serine protease inhibitors. The protein is a potent inhibitor specific for HGF activator and is thought to be involved in the regulation of the proteolytic activation of HGF in injured tissues. Alternative splicing results in multiple variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: HAI-1; hepatocyte growth factor activator inhibitor 1; Hepatocyte growth factor activator inhibitor type 1; hepatocyte growth factor activator inhibitor-1; Kunitz-type protease inhibitor 1; serine protease inhibitor, Kunitz type 1
Gene Aliases: HAI; HAI-1; HAI1; MANSC2; SPINT1; UNQ223/PRO256
UniProt ID: (Human) O43278, (Mouse) Q9R097
Entrez Gene ID: (Human) 6692, (Dog) 487501, (Mouse) 20732, (Rat) 311331
neural tube closure
negative regulation of endopeptidase activity
extracellular matrix organization
positive regulation of glial cell differentiation
branching involved in labyrinthine layer morphogenesis
placenta blood vessel development
cellular response to BMP stimulus
negative regulation of neural precursor cell proliferation
embryonic placenta development
negative regulation of peptidase activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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