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Abnova
SPOCK1 Polyclonal Antibody, MaxPab™
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Product Details
H00006695-B02P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SPOCK1 (AAH30691.1, 1 a.a. approximately 439 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MPAIAVLAAA AAAWCFLQVE SRHLDALAGG AGPNHGNFLD NDQWLSTVSQ YDRDKYWNRF RDDDYFRNWN PNKPFDKALD PSKDPCLKVK CSPHKVCVTQ DYQTALCVSR KHLLPRQKKG NVAQKHWVGP SNLVKCKPCP VAQSAMVCGS DGHSYTSKCK LEFHACSTGK SLATLCDGPC PCLPEPEPPK HKAERSACTD KELRNLASRL KDWFGALHED ANRVIKPTSS NTAQGRFDTS ILPICKDSLG WMFNKLDMNY DLLLDPSEIN AIYLDKYEPC IKPLFNSCDS FKDGKLSNNE WCYCFQKPGG LPCQNEMNRI QKLSKGKSLL GAFIPRCNEE GYYKATQCHG STGQCWCVDK YGNELAGSRK QGAVSCEEEQ ETSGDFGSGG SVVLLDDLEY ERELGPKDKE GKLRVHTRAV TEDDEDEDDD KEDEVGYIW
Target Information
SPOCK1, also known as Testican-1, is a gene located on chromosome 5q31.2, encoding a member of the proteoglycan family characterized by containing multiple domains that facilitate interactions with other extracellular matrix proteins. SPOCK1 is primarily expressed in various tissues, including the brain and reproductive organs, where it plays crucial roles in modulating cell adhesion, migration, and matrix remodeling. Functionally, SPOCK1 contributes to the regulation of extracellular matrix composition, influencing processes such as tissue development and wound healing. In the context of cancer, SPOCK1 is often upregulated, promoting tumor progression and metastasis by enhancing cancer cell motility and invasiveness. Its involvement in these pathological mechanisms makes SPOCK1 a potential biomarker for cancer prognosis and a target for therapeutic intervention. Research continues to unravel SPOCK1's diverse biological activities and its impact on cellular architecture and disease progression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ37170; Protein SPOCK; Testican-1
Gene Aliases: SPOCK; SPOCK1; TESTICAN; TIC1; TICN1
UniProt ID: (Human) Q08629
Entrez Gene ID: (Human) 6695
regulation of cell growth
neuron migration
cell adhesion
signal transduction
nervous system development
negative regulation of cell-substrate adhesion
negative regulation of endopeptidase activity
negative regulation of neuron projection development
central nervous system neuron differentiation
neurogenesis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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