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Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, leading most often to their proteasomal degradation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: HIB homolog 1; PDX-1 C-terminal-interacting factor 1; Roadkill homolog 1; speckle type POZ protein; Speckle-type POZ protein
Gene Aliases: AI315626; BTBD32; Pcif1; SPOP; TEF2
UniProt ID: (Human) O43791, (Mouse) Q6ZWS8
Entrez Gene ID: (Human) 8405, (Mouse) 20747, (Rat) 287643
Molecular Function:
actin family cytoskeletal protein
cytoskeletal protein
hydrolase
non-motor actin binding protein
protease
serine protease
transcription cofactor
transcription factor
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