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Exalpha
SPT16 NT Polyclonal Antibody
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Product Details
X1583P
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein consisting of amino acids 1-329 of the human SPT16 protein conjugated to KLH.
Conjugate
Form
Liquid
Concentration
0.5-2 mg/mL
Purification
Ammonium sulfate precipitation
Storage buffer
PBS
Contains
0.08% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Positive control: Recombinant proteins conjugated to OVA, GST, His tags and other.
Target Information
Transcription of protein-coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II. However, this minimal system cannot transcribe DNA packaged into chromatin, indicating that accessory factors may facilitate access to DNA. One such factor, FACT, interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT is composed of an 80 kDa subunit and a 140 kDa subunit; this gene encodes the 140 kDa subunit.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Chromatin-specific transcription elongation factor 140 kDa subunit; facilitates chromatin remodeling 140 kDa subunit; Facilitates chromatin transcription complex subunit SPT16; FACT; FACT 140 kDa subunit; FACT complex subunit SPT16; FACTp140; FLJ10857; FLJ14010; FLJ34357; HGNC:11465; hSPT16; suppressor of Ty 16 homolog
Gene Aliases: CDC68; FACT140; FACTP140; SPT16; SPT16/CDC68; Supt16; SUPT16H
UniProt ID: (Human) Q9Y5B9, (Mouse) Q920B9
Entrez Gene ID: (Human) 11198, (Mouse) 114741
DNA replication
DNA repair
nucleosome disassembly
transcription from RNA polymerase II promoter
transcription elongation from RNA polymerase II promoter
positive regulation of DNA-templated transcription, elongation
regulation of signal transduction by p53 class mediator
transcription, DNA-templated
regulation of transcription, DNA-templated
cellular response to DNA damage stimulus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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