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Bethyl Laboratories
SPTBN1 Polyclonal Antibody
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Product Details
IHC-00157
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residues 2150 and 2200 of Human Spectrin Non-Erythroid Beta 1.
Conjugate
Form
Liquid
Concentration
0.25 mg/mL
Amount
25 µg
Purification
Antigen affinity chromatography
Storage buffer
TBS, pH 7.0 to 8.0, with 0.1% BSA
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
Spectrin (Sp), the most abundant of the erythrocyte membrane skeleton proteins, helps these cells maintain their characteristic biconcave shape while remaining flexible and elastic. Erythrocyte Sp is a heterodimer composed of a 280 kDa alpha subunit and a 246 kDa beta subunit which associate in a side-to-side, antiparallel configuration to form a 100 nm rod-like structure. Sp in other tissues may be composed of distinct but homologous alpha and beta subunits, sometimes referred to as fodrin. A newly introduced nomenclature designates the Sp subunits of the erythrocyte as alpha-1 and beta-1, and the fodrin subunits as alpha-2 and beta-2. Alternatively spliced forms of each are designated as epsilon-1, epsilon-2, etc. (e. g. beta-1 epsilon-1).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: beta-fodrin; beta-G spectrin; Beta-II spectrin; beta-spectrin 2; beta-spectrin II; beta-spectrin non-erythrocytic 1; cytoskeleton protein; embryonic liver beta-fodrin; embryonic liver fodrin beta chain; epididymis luminal protein 102; Fodrin beta chain; spectrin beta chain, brain 1; Spectrin beta chain, non-erythrocytic 1; Spectrin, non-erythroid beta chain 1; SPNB2; unnamed protein product
Gene Aliases: betaSpII; DDISBA; ELF; HEL102; SPTB2; SPTBN1
UniProt ID: (Human) Q01082
Entrez Gene ID: (Human) 6711
mitotic cytokinesis
plasma membrane organization
central nervous system development
vesicle-mediated transport
central nervous system formation
actin cytoskeleton organization
positive regulation of interleukin-2 production
Golgi to plasma membrane protein transport
actin filament capping
regulation of SMAD protein import into nucleus
membrane assembly
protein localization to plasma membrane
regulation of protein localization to plasma membrane
positive regulation of protein localization to plasma membrane
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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