Invitrogen

SPTLC1 Polyclonal Antibody

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SPTLC1 Antibody in Immunohistochemistry (IHC) — Immunohistochemistry of SPT1 in human lung tissue with SPTLC1 Polyclonal Antibody (Product # PA5-21141) at 5 µg/mL.

SPTLC1 Antibody in Western Blot (WB) — Western Blot analysis of SPT1 in (A) A549 and (B) HeLa cell lysate with SPTLC1 Polyclonal Antibody (Product # PA5-21141) at 1 µg/mL.

Product Details

PA5-21141

Applications	Tested Dilution	Publications
Western Blot (WB)	1 µg/mL	-
Immunohistochemistry (IHC)	5 µg/mL	-

Product Specifications
Species Reactivity	Human
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	A 17 amino acid peptide near the carboxy terminus of human SPT1. View antigen
Conjugate	Unconjugated
Form	Liquid
Concentration	1 mg/mL
Purification	Antigen affinity chromatography
Storage buffer	PBS
Contains	0.02% sodium azide
Storage conditions	Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
RRID	AB_11154242

Product Specific Information

A suggested positive control is human lung tissue lysate.

PA5-21141 can be used with blocking peptide PEP-1255.

Target Information

Serine palmitoyltransferase (SPT) is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: hLCB1; HSAN; LCB 1; Long chain base biosynthesis protein 1; MGC14645; RP11-118F2.1; serine C-palmitoyltransferase; Serine palmitoyltransferase 1; serine palmitoyltransferase, long chain base subunit 1; Serine-palmitoyl-CoA transferase 1; SPT 1

Gene Aliases: HSAN1; HSN1; LBC1; LCB1; SPT1; SPTI; SPTLC1

UniProt ID: (Human) O15269

Entrez Gene ID: (Human) 10558

Molecular Function: transaminase