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Invitrogen
SPTLC1 Polyclonal Antibody
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Product Details
PA5-21141
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A 17 amino acid peptide near the carboxy terminus of human SPT1.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
A suggested positive control is human lung tissue lysate.
PA5-21141 can be used with blocking peptide PEP-1255.
Target Information
Serine palmitoyltransferase (SPT) is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: hLCB1; HSAN; LCB 1; Long chain base biosynthesis protein 1; MGC14645; RP11-118F2.1; serine C-palmitoyltransferase; Serine palmitoyltransferase 1; Serine-palmitoyl-CoA transferase 1; SPT 1; unnamed protein product
Gene Aliases: ALS27; HSAN1; HSN1; LBC1; LCB1; SPT1; SPTI; SPTLC1
UniProt ID: (Human) O15269
Entrez Gene ID: (Human) 10558
lipid metabolic process
sphingolipid metabolic process
sphingomyelin biosynthetic process
sphingolipid biosynthetic process
amide biosynthetic process
sphinganine biosynthetic process
sphingosine biosynthetic process
ceramide biosynthetic process
positive regulation of lipophagy
regulation of fat cell apoptotic process
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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