Immunogen sequence: MANPGGGAVCN GKLHNHKKQS NGSQSRNCTK NGIVKEAQQN GKPHFYDKLI VESFEEA
Highest antigen sequence identity to the following orthologs - mouse 53%, rat 52%.
Serine palmitoyltransferase (SPT). The heterodimer formed with LCB1/SPTLC1 constitutes the catalytic core. The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference. The SPTLC1-SPTLC3-SPTSSA isozyme uses both C14-CoA and C16-CoA as substrates, while the SPTLC1-SPTLC3-SPTSSB has the ability to use a broader range of acyl-CoAs without apparent preference.
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Protein Aliases: LCB 3; LCB2b; Long chain base biosynthesis protein 2b; Long chain base biosynthesis protein 3; Serine palmitoyltransferase 3; serine palmitoyltransferase, long chain base subunit 2-like (aminotransferase 2); serine palmitoyltransferase, long chain base subunit 3; Serine-palmitoyl-CoA transferase 3; SPT 3
Gene Aliases: C20orf38; dJ718P11; dJ718P11.1; hLCB2b; LCB2B; LCB3; SPT3; SPTLC2L; SPTLC3
UniProt ID: (Human) Q9NUV7
Entrez Gene ID: (Human) 55304