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Proteintech
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Immunogen sequence: GRPTASVIP SGVEWIKARV TELNPDKNCI HTDDDEKISY RYLIIALGIQ LDYEKIKGLP EGFAHPKIGS NYSVKTVEKT WKALQDFKEG NAIFTFPNTP VKCAGAPQKI MYLSEAYFRK TGKRSKANII FNTSLGAIFG VKKYADALQE IIQERNLTVN YKKNLIEVRA DKQEAVFENL DKPGETQVIS YEMLHVTPPM SPPDVLKTSP VADAAGWVDV DKETLQHRRY PNVFGIGDCT NLPTSKTAAA VAAQSGILDR TISVIMKNQT PTKKYDGYTS CPLVTGYNRV ILAEFDYKAE PLETFPFDQS KERLSMYLMK ADLMPFLYWN MMLRGYWGGP AFLRKLFHLG MS (100-450 aa encoded by BC016836)
SQRDL (Sulfide: quinone oxidoreductase, mitochondrial) catalyzes the oxidation of hydrogen sulfide, with the help of a quinone. Although the SQRDL precursor protein displays a molecular weight of 50 kDa, a prominent band at about 46 kDa is detected by western blot. This discrepancy reflects the cleavage of an N-terminal targeting sequence of 4 kDa during the import of the protein into the mitochondria. SQRDL is one of the enzymes involved in H2S signaling in a discrete population of neurons, oligodendrocytes, and endothelial cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: flavo-binding protein; SQOR; sulfide dehydrogenase like; Sulfide dehydrogenase-like; Sulfide quinone oxidoreductase; Sulfide:quinone oxidoreductase, mitochondrial
Gene Aliases: 0610039J17Rik; 4930557M22Rik; Cc2-17; CGI-44; PRO1975; SQOR; SQRDL
UniProt ID: (Human) Q9Y6N5, (Mouse) Q9R112
Entrez Gene ID: (Human) 58472, (Rat) 691966, (Mouse) 59010
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