Search

  • お問い合わせ一覧​
  • クイックオーダー

Invitrogen

SQSTM1 Polyclonal Antibody

View all (79) SQSTM1 antibodies

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

Datasheet
Certificates
Protocols
Questions & Answers
Tech Support
Datasheet
Certificates
Protocols
Questions & Answers
Tech Support
Datasheet
Certificates
Protocols
Questions & Answers
Tech Support
Additional Information:
{{banner.description}}
{{$ctrl.isSkuNotesCollapsed ? 'View more' : 'View less'}}
SQSTM1 Polyclonal Antibody

Product Details

PA5-12092

Applications
Tested Dilution
Publications

Western Blot (WB)

1:1,000-1:2,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:100
-

Immunocytochemistry (ICC/IF)

1:50-1:100
-
Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated synthetic peptide between 317-346 amino acids of human SQSTM1 (p62)
3D Epitope / Immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Purification

Antigen affinity chromatography, Protein A

Storage buffer

PBS, pH 7.4

Contains

0.09% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2196012

Product Specific Information

This antibody is predicted to react with mouse and rat based on sequence homology.

Target Information

This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

References (0)

Have you cited this product in a publication?
Let us know so we can reference it here.
Cite this product

Bioinformatics

Protein Aliases: autophagy receptor p62; EBI3-associated protein of 60 kDa; EBI3-associated protein p60; EBIAP; oxidative stress induced; oxidative stress induced like; p62; p62 transcript variant 4; p62 transcript variant 5; phosphotyrosine independent ligand for the Lck SH2 domain p62; Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa; Sequestosome-1; STONE14; Ubiquitin-binding protein p62; unnamed protein product

View more View less

Gene Aliases: A170; DMRV; EBIAP; FTDALS3; NADGP; ORCA; OSF-6; Osi; OSIL; p60; p62; p62B; PDB3; SQSTM1; STAP; STONE14; ZIP3

View more View less

UniProt ID: (Human) Q13501, (Mouse) Q64337

View more View less

Entrez Gene ID: (Human) 8878, (Mouse) 18412

View more View less

Function(s)
protein kinase C binding protein binding zinc ion binding enzyme binding protein kinase binding protein binding, bridging receptor tyrosine kinase binding ubiquitin protein ligase binding ionotropic glutamate receptor binding signaling receptor activity SH2 domain binding identical protein binding ubiquitin binding macromolecular complex binding metal ion binding K63-linked polyubiquitin binding ubiquitin-dependent protein binding protein sequestering activity molecular sequestering activity molecular condensate scaffold activity transcription cofactor activity protein homodimerization activity
Process(es)
negative regulation of transcription from RNA polymerase II promoter mitophagy mitophagy pexophagy temperature homeostasis immune system process response to ischemia transcription from RNA polymerase II promoter ubiquitin-dependent protein catabolic process protein import into nucleus autophagy apoptotic process endosome organization protein localization positive regulation of autophagy regulation of mitochondrion organization endosomal transport macroautophagy cell differentiation protein catabolic process negative regulation of protein ubiquitination cellular response to stress toll-like receptor 4 signaling pathway negative regulation of toll-like receptor 4 signaling pathway intracellular signal transduction aggrephagy positive regulation of apoptotic process regulation of I-kappaB kinase/NF-kappaB signaling positive regulation of transcription from RNA polymerase II promoter regulation of Ras protein signal transduction regulation of protein complex stability brown fat cell proliferation protein K63-linked ubiquitination protein targeting to vacuole involved in autophagy energy homeostasis response to mitochondrial depolarisation negative regulation of ferroptosis membraneless organelle assembly positive regulation of long-term synaptic potentiation positive regulation of protein localization to plasma membrane protein localization to perinuclear region of cytoplasm positive regulation of protein phosphorylation positive regulation of macroautophagy protein heterooligomerization mitophagy in response to mitochondrial depolarization regulation of nucleic acid-templated transcription
guarantee_icon

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more
help_icon

We're here to help

Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

Contact tech support