Product References
Long Non-Coding RNA TUG1 Attenuates Insulin Resistance in Mice with Gestational Diabetes Mellitus via Regulation of the MicroRNA-328-3p/SREBP-2/ERK Axis.
Diabetes & metabolism journal
Tang X,Qin Q,Xu W,Zhang X
Wed Mar 01 00:00:00 EST 2023
Long Non-Coding RNA TUG1 Attenuates Insulin Resistance in Mice with Gestational Diabetes Mellitus via Regulation of the MicroRNA-328-3p/SREBP-2/ERK Axis.
Diabetes & metabolism journal
Tang X,Qin Q,Xu W,Zhang X
Wed Mar 01 00:00:00 EST 2023
Tilianin improves lipid profile and alleviates atherosclerosis in ApoE-/- mice through up-regulation of SREBP2-mediated LDLR expression.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Du Y,Xi M,Li Y,Zheng R,Ding X,Li X,Zhang X,Wang L,Xing J,Hong B
Sun Jan 01 00:00:00 EST 2023
Decreased Imiquimod-Induced Psoriasis-Like Skin Inflammation in a Novel MvdF250S/+ Knock-In Mouse Model.
Inflammation
La Y,Wong W,Peng K,Tian Z,Pan J,Sun R,Luan J,Yan K,Zhang Q,Zhang Z
Tue Aug 01 00:00:00 EDT 2023
Lipophagy-mediated cholesterol synthesis inhibition is required for the survival of hepatocellular carcinoma under glutamine deprivation.
Redox biology
Kong Y,Wu M,Wan X,Sun M,Zhang Y,Wu Z,Li C,Liang X,Gao L,Ma C,Yue X
Sat Jul 01 00:00:00 EDT 2023
Lipophagy-mediated cholesterol synthesis inhibition is required for the survival of hepatocellular carcinoma under glutamine deprivation.
Redox biology
Kong Y,Wu M,Wan X,Sun M,Zhang Y,Wu Z,Li C,Liang X,Gao L,Ma C,Yue X
Sat Jul 01 00:00:00 EDT 2023
MiR-122-5p regulates the mevalonate pathway by targeting p53 in non-small cell lung cancer.
Cell death & disease
Zheng YK,Zhou ZS,Wang GZ,Tu JY,Cheng HB,Ma SZ,Ke C,Wang Y,Jian QP,Shu YH,Wu XW
Sat Apr 01 00:00:00 EDT 2023
Targeting PCSK9 reduces cancer cell stemness and enhances antitumor immunity in head and neck cancer.
iScience
Yang QC,Wang S,Liu YT,Song A,Wu ZZ,Wan SC,Li HM,Sun ZJ
Fri Jun 16 00:00:00 EDT 2023
The Scap-SREBP1-S1P/S2P lipogenesis signal orchestrates the homeostasis and spatiotemporal activation of NF-κB.
Cell reports
Fei X,Huang J,Li F,Wang Y,Shao Z,Dong L,Wu Y,Li B,Zhang X,Lv B,Zhao Y,Weng Q,Chen K,Zhang M,Yang S,Zhang C,Zhang M,Li W,Ying S,Sun Q,Chen Z,Shen H
Tue Jun 27 00:00:00 EDT 2023
The p97-UBXD8 complex regulates ER-Mitochondria contact sites by altering membrane lipid saturation and composition.
Nature communications
Ganji R,Paulo JA,Xi Y,Kline I,Zhu J,Clemen CS,Weihl CC,Purdy JG,Gygi SP,Raman M
Mon Feb 06 00:00:00 EST 2023
Resveratrol Modulates the Redox Response and Bile Acid Metabolism to Maintain the Cholesterol Homeostasis in Fish Megalobrama amblycephala Offered a High-Carbohydrate Diet.
Antioxidants (Basel, Switzerland)
Ge Y,Zhang L,Chen W,Sun M,Liu W,Li X
Tue Jan 03 00:00:00 EST 2023
LATS-regulated nuclear-cytoplasmic translocation of SREBP2 inhibits hepatocellular carcinoma cell migration and invasion via epithelial-mesenchymal transition.
Molecular carcinogenesis
Zhang F,Gao J,Liu X,Sun Y,Liu L,Hu B,Wang Z,Shi J,Guo W,Zhang S
Sat Jul 01 00:00:00 EDT 2023
CD36 promotes de novo lipogenesis in hepatocytes through INSIG2-dependent SREBP1 processing.
Molecular metabolism
Zeng H,Qin H,Liao M,Zheng E,Luo X,Xiao A,Li Y,Chen L,Wei L,Zhao L,Ruan XZ,Yang P,Chen Y
Tue Mar 01 00:00:00 EST 2022
Nrf1 is an indispensable redox-determining factor for mitochondrial homeostasis by integrating multi-hierarchical regulatory networks.
Redox biology
Hu S,Feng J,Wang M,Wufuer R,Liu K,Zhang Z,Zhang Y
Tue Nov 01 00:00:00 EDT 2022
Design, synthesis and neurite outgrowth activity of novel ganglioside GM1 derivatives by remodeling of the fatty acid moiety.
European journal of medicinal chemistry
Chen X,Jin X,Huang F,Wang J,Cao X,Wang PG,Feng Y,Jiang F,Yang G
Sat Nov 05 00:00:00 EDT 2022
The Accelerated Progression of Atherosclerosis Correlates with Decreased miR-33a and miR-21 and Increased miR-122 and miR-3064-5p in Circulation and the Liver of ApoE-/- Mice with Streptozocin (STZ)-Induced Type 2 Diabetes.
Current issues in molecular biology
Luo HY,Li G,Liu YG,Wei YH,Chen JB,Gu XF,Tang JQ,Zhao Y,Su CH,Xiao LY,Xiong F,Zheng ZD,Wang SY,Zha LY
Thu Oct 13 00:00:00 EDT 2022
Inhibition of Stearoyl-CoA Desaturase 1 Potentiates Anti-tumor Activity of Amodiaquine in Non-small Cell Lung Cancer.
Biological & pharmaceutical bulletin
Hu X,Xiang J,Li Y,Xia Y,Xu S,Gao X,Qiao S
Fri Apr 01 00:00:00 EDT 2022
Osthole Increases the Sensitivity of Liver Cancer to Sorafenib by Inhibiting Cholesterol Metabolism.
Nutrition and cancer
Fan K,Huang H,Zhao Y,Xie T,Zhu ZY,Xie ML
Thu Sep 08 00:00:00 EDT 2022
Increased LDL receptor by SREBP2 or SREBP2-induced lncRNA LDLR-AS promotes triglyceride accumulation in fish.
iScience
Cao X,Fang W,Li X,Wang X,Mai K,Ai Q
Fri Jul 15 00:00:00 EDT 2022
PTPRO represses colorectal cancer tumorigenesis and progression by reprogramming fatty acid metabolism.
Cancer communications (London, England)
Dai W,Xiang W,Han L,Yuan Z,Wang R,Ma Y,Yang Y,Cai S,Xu Y,Mo S,Li Q,Cai G
Thu Sep 01 00:00:00 EDT 2022
VIP plasma levels associate with survival in severe COVID-19 patients, correlating with protective effects in SARS-CoV-2-infected cells.
Journal of leukocyte biology
Temerozo JR,Sacramento CQ,Fintelman-Rodrigues N,Pão CRR,de Freitas CS,Dias SSG,Ferreira AC,Mattos M,Soares VC,Teixeira L,Azevedo-Quintanilha IG,Hottz ED,Kurtz P,Bozza FA,Bozza PT,Souza TML,Bou-Habib DC
Sun May 01 00:00:00 EDT 2022
Fine-Tuning of Cholesterol Homeostasis Controls Erythroid Differentiation.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Lu Z,Huang L,Li Y,Xu Y,Zhang R,Zhou Q,Sun Q,Lu Y,Chen J,Shen Y,Li J,Zhao B
Sat Jan 01 00:00:00 EST 2022
SOAT1 Promotes Gastric Cancer Lymph Node Metastasis Through Lipid Synthesis.
Frontiers in pharmacology
Zhu T,Wang Z,Zou T,Xu L,Zhang S,Chen Y,Chen C,Zhang W,Wang S,Ding Q,Xu G
Fri Nov 19 00:00:00 EST 2021
LPCAT1 reprogramming cholesterol metabolism promotes the progression of esophageal squamous cell carcinoma.
Cell death & disease
Tao M,Luo J,Gu T,Yu X,Song Z,Jun Y,Gu H,Han K,Huang X,Yu W,Sun S,Zhang Z,Liu L,Chen X,Zhang L,Luo C,Wang Q
Mon Sep 13 00:00:00 EDT 2021
LncRNA PCA3 promotes antimony-induced lipid metabolic disorder in prostate cancer by targeting MIR-132-3 P/SREBP1 signaling.
Toxicology letters
Guo S,Zhang Y,Wang S,Yang T,Ma B,Li X,Zhang Y,Jiang X
Wed Sep 15 00:00:00 EDT 2021
Xinnaokang improves cecal microbiota and lipid metabolism to target atherosclerosis.
Letters in applied microbiology
Yang R,Yin D,Yang D,Liu X,Zhou Q,Pan Y,Li J,Li S
Wed Dec 01 00:00:00 EST 2021
The Chromatin Remodeling Protein BRG1 Regulates SREBP Maturation by Activating SCAP Transcription in Hepatocytes.
Frontiers in cell and developmental biology
Kong M,Zhu Y,Shao J,Fan Z,Xu Y
Tue Mar 16 00:00:00 EDT 2021
A Novel c-MET-Targeting Antibody-Drug Conjugate for Pancreatic Cancer.
Frontiers in oncology
Jin Y,Zhang Z,Zou S,Li F,Chen H,Peng C,Deng X,Wen C,Shen B,Zhan Q
Tue Apr 06 00:00:00 EDT 2021
Novel SREBP1 inhibitor cinobufotalin suppresses proliferation of hepatocellular carcinoma by targeting lipogenesis.
European journal of pharmacology
Meng H,Shen M,Li J,Zhang R,Li X,Zhao L,Huang G,Liu J
Sun Sep 05 00:00:00 EDT 2021
Novel SREBP1 inhibitor cinobufotalin suppresses proliferation of hepatocellular carcinoma by targeting lipogenesis.
European journal of pharmacology
Meng H,Shen M,Li J,Zhang R,Li X,Zhao L,Huang G,Liu J
Sun Sep 05 00:00:00 EDT 2021
Investigation of the Lipid-Lowering Mechanisms and Active Ingredients of Danhe Granule on Hyperlipidemia Based on Systems Pharmacology.
Frontiers in pharmacology
Chen K,Ma Z,Yan X,Liu J,Xu W,Li Y,Dai Y,Zhang Y,Xiao H
Thu Apr 14 00:00:00 EDT 2022
Recombinant human lactoferrin attenuates the progression of hepatosteatosis and hepatocellular death by regulating iron and lipid homeostasis in ob/ob mice.
Food & function
Guo C,Xue H,Guo T,Zhang W,Xuan WQ,Ren YT,Wang D,Chen YH,Meng YH,Gao HL,Zhao P
Sat Aug 01 00:00:00 EDT 2020
The role of AMPKα2 in the HFD-induced nonalcoholic steatohepatitis.
Biochimica et biophysica acta. Molecular basis of disease
Zhang X,Liu S,Zhang C,Zhang S,Yue Y,Zhang Y,Chen L,Yao Z,Niu W
Thu Oct 01 00:00:00 EDT 2020
Brahma Related Gene 1 (Brg1) Regulates Cellular Cholesterol Synthesis by Acting as a Co-factor for SREBP2.
Frontiers in cell and developmental biology
Fan Z,Kong M,Li M,Hong W,Fan X,Xu Y
Mon Sep 28 00:00:00 EDT 2020
Vitamin E Ameliorates Lipid Metabolism in Mice with Nonalcoholic Fatty Liver Disease via Nrf2/CES1 Signaling Pathway.
Digestive diseases and sciences
He W,Xu Y,Ren X,Xiang D,Lei K,Zhang C,Liu D
Fri Nov 01 00:00:00 EDT 2019