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|Tested species reactivity||Hamster, Human, Mouse, Rat|
|Published species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Human SREBP1 protein sequence (between residues 700-800) [Uniprot# P36956].|
|Purification||Antigen affinity chromatography|
|Storage buffer||tris glycine with 150mM NaCl|
|Contains||0.05% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||2 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Western Blot (WB)||See 1 publications below|
This antibody is predicted to react with porcine based on 100% sequence homology.
This antibody has 94% sequence homology with bovine, 88% sequence homology with zebrafish and 70% sequence homology with chicken.
Suggested positive control: human liver lysate.
SREBP (Sterol Regulatory Element Binding Protein) 1 and 2 are transcription factors which participate in the control of cholesterol homeostasis. SREBP proteins, which are attached to the endoplasmic reticulum and nuclear envelope, are proteolytically cleaved and thus activated in response to conditions of low cellular sterol. SREBPs may also play some role in the apoptotic processes
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Caveolin-1 protects B6129 mice against Helicobacter pylori gastritis.
PA1-46142 was used in western blot to study the ability of caveolin-1 to protect against gastritis in Helicobacter pylori-infected mice
|Hitkova I,Yuan G,Anderl F,Gerhard M,Kirchner T,Reu S,Röcken C,Schäfer C,Schmid RM,Vogelmann R,Ebert MP,Burgermeister E||PLoS pathogens (9:null)||2013|
adipocyte determination- and differentiation-dependent factor 1; bHLHd1; class D basic helix-loop-helix protein 1; nt-SREBP1; SREBP-1c; SREBP1; sterol regulatory element-binding protein 1
ADD-1; ADD1; BHLHD1; D630008H06; SREBF1; SREBP-1; SREBP-1a; SREBP-1c; SREBP1; SREBP1a; SREBP1c