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The protein encoded by this gene is a GTPase activator, working with the GTPase CDC42 to negatively regulate neuronal migration. The encoded protein interacts with the transmembrane receptor ROBO1 to inactivate CDC42.
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Protein Aliases: Rho GTPase-activating protein 13; SLIT-ROBO Rho GTPase-activating protein 1; srGAP1
Gene Aliases: ARHGAP13; KIAA1304; NMTC2; SRGAP1
UniProt ID: (Human) Q7Z6B7
Entrez Gene ID: (Human) 57522
Molecular Function: GTPase-activating protein