Invitrogen

SRGAP3 Polyclonal Antibody

Advanced Verification

This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.

View all (4) SRGAP3 antibodies

Datasheet

Protocols

Questions & Answers

Tech Support

Datasheet

Protocols

Questions & Answers

Tech Support

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SRGAP3 Antibody in Immunocytochemistry (ICC/IF) — Immunofluorescent staining of SRGAP3 in human cell line RT4 using a SRGAP3 Polyclonal Antibody (Product # PA5-60607) shows localization to nucleoplasm.

SRGAP3 Antibody in Immunohistochemistry (IHC) — Immunohistochemical staining of SRGAP3 in human cerebral cortex, lymph node, testis and urinary bladder using SRGAP3 Polyclonal Antibody (Product # PA5-60607) (A) shows similar protein distribution across tissues to an independent SRGAP3 Polyclonal Antibody (B).

SRGAP3 Antibody — Relative expression in different tissues in IHC: Detection of differential expression levels of SRGAP3 demonstrates antibody specificity. Immunohistochemical analysis of SRGAP3 using anti-SRGAP3 Polyclonal Antibody (Product # PA5-60607), shows significant staining of SRGAP3 in human fallopian tube and shows minimal or weak staining in human colon tissues. The relative expression levels of SRGAP3 within each tissue is shown using RNA-Seq. {RE}

Product Details

PA5-60607

Applications	Tested Dilution	Publications
Immunohistochemistry (IHC)	1:50-1:200	-
Immunocytochemistry (ICC/IF)	0.25-2 µg/mL	-

Product Specifications
Species Reactivity	Human
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	Recombinant protein corresponding to Human SRGAP3 View antigen
Conjugate	Unconjugated
Form	Liquid
Concentration	0.2 mg/mL
Purification	Antigen affinity chromatography
Storage buffer	PBS, pH 7.2, with 40% glycerol
Contains	0.02% sodium azide
Storage conditions	Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
RRID	AB_2647922

Product Specific Information

Immunogen sequence: RIESPEKRRM ATFGSAGSIN YPDKKALSEG HSMRSTCGST RHSSLGDHKS LEAEALAEDI EKTMSTA

Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 97%.

Target Information

GTPase-activating protein for RAC1 and perhaps Cdc42, but not for RhoA small GTPase. May attenuate RAC1 signaling in neurons. [UniProt]

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Mental disorder-associated GAP; Rho GTPase-activating protein 14; SLIT-ROBO Rho GTPase activating protein 2; SLIT-ROBO Rho GTPase-activating protein 3; srGAP3; WAVE-associated Rac GTPase activating protein; WAVE-associated Rac GTPase-activating protein; WRP

Gene Aliases: ARHGAP14; KIAA0411; KIAA1156; MEGAP; SRGAP2; SRGAP3; WRP

UniProt ID: (Human) O43295

Entrez Gene ID: (Human) 9901

Molecular Function: GTPase-activating protein