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Product Details
PA5-53420
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human SRPK1. Recombinant protein control fragment (Product #RP-91437).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2647928
Product Specific Information
Immunogen sequence: QEIEEMEKES GPGQKRPNKQ EESESPVERP LKENPPNKMT QEKLEESSTI GQDQTLMERD TEGGAAEINC NGVIEVINYT QNSNNETLRH KEDLHNANDC DVQNLNQESS FLSS
Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 85%.
Target Information
SRPK1 is a serine/threonine kinase that plays a role in the regulation of both constitutive and alternative splicing by regulating intracellular localization of splicing factors. SRPK1 localizes to the nucleus and the cytoplasm. It is thought to play a role in regulation of both constitutive and alternative splicing by regulating intracellular localization of splicing factors. A second alternatively spliced transcript variant for this gene has been described, but its full length nature has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: OTTHUMP00000016277; Serine/arginine-rich protein-specific kinase 1; serine/arginine-rich splicing factor kinase 1; serine/threonine-protein kinase SRPK1; SFRS protein kinase 1; SR-protein-specific kinase 1; SRPK1; SRSF protein kinase 1
Gene Aliases: SFRSK1; SRPK1
UniProt ID: (Human) Q96SB4
Entrez Gene ID: (Human) 6732
mRNA processing
protein phosphorylation
chromosome segregation
RNA splicing
viral process
sperm chromatin condensation
intracellular signal transduction
positive regulation of viral genome replication
negative regulation of viral genome replication
innate immune response
regulation of mRNA splicing, via spliceosome
regulation of mRNA processing
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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