Invitrogen

SRR Polyclonal Antibody

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SRR Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunocytochemical analysis of paraffin-embeded SRR in human brain tissue using a SRR Polyclonal antibody (Product # PA5-112725) at a dilution of 1:100.

SRR Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunocytochemical analysis of paraffin-embeded SRR in human heart tissue using a SRR Polyclonal antibody (Product # PA5-112725) at a dilution of 1:100.

SRR Antibody in Western Blot (WB) — Western Blot analysis of SRR in multiple sample types using a SRR polyclonal antibody (Product # PA5-112725) at a concentration of 3 µg/ml. A goat anti rabbit polyclonal secondary antibody was used at a dilution of 1:50,000. Sample types that were tested include: Mouse heart tissue, Mouse brain tissue .

Product Details

PA5-112725

Applications	Tested Dilution	Publications
Western Blot (WB)	1:500-1:5,000	-
Immunohistochemistry (Paraffin) (IHC (P))	1:20-1:200	-
ELISA (ELISA)	Assay-dependent	-

Product Specifications
Species Reactivity	Human, Mouse
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	Recombinant Human Serine racemase protein (1-340AA) View immunogen
Conjugate	Unconjugated
Form	Liquid
Concentration	3 mg/mL
Purification	Protein G
Storage buffer	PBS, pH 7.4, with 50% glycerol
Contains	0.03% ProClin 300
Storage conditions	-20°C or -80°C if preferred
RRID	AB_2867460

Target Information

SRR (serine racemase) catalyzes the synthesis of D-serine from L-serine.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: D-serine ammonia-lyase; D-serine dehydratase; L-serine ammonia-lyase; L-serine dehydratase; Serine racemase

Gene Aliases: ILV1; ISO1; SRR; Srs

UniProt ID: (Human) Q9GZT4, (Mouse) Q9QZX7

Entrez Gene ID: (Human) 63826, (Mouse) 27364

Molecular Function: epimerase/racemase isomerase metabolite interconversion enzyme

L-serine metabolic process brain development aging serine family amino acid metabolic process response to lipopolysaccharide response to drug pyruvate biosynthetic process response to morphine protein homotetramerization D-serine metabolic process D-serine biosynthetic process cellular amino acid metabolic process metabolic process

Process(es)

magnesium ion binding L-serine ammonia-lyase activity calcium ion binding ATP binding D-serine ammonia-lyase activity glycine binding threonine racemase activity PDZ domain binding pyridoxal phosphate binding serine racemase activity protein homodimerization activity nucleotide binding catalytic activity protein binding lyase activity isomerase activity metal ion binding