Immunogen sequence: LKVDNLTYRT SPDSLRRVFE KYGRVGDVYI PR
Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 97%.
The protein encoded by this gene is a member of a family of RIM-binding proteins. RIMs are active zone proteins that regulate neurotransmitter release. This gene has been found fused to the receptor-type tyrosine kinase gene RET by gene rearrangement due to the translocation t(10;12)(q11;p13). Multiple transcript variants encoding different isoforms have been found for this gene.
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Protein Aliases: Protein PR264; SC-35; Serine/arginine-rich splicing factor 2; SFRS2; Splicing component, 35 kDa; Splicing factor SC35; Splicing factor, arginine/serine-rich 2; SR splicing factor 2
Gene Aliases: PR264; SC-35; SC35; SFRS2; SFRS2A; SRp30b; SRSF2
UniProt ID: (Human) Q01130
Entrez Gene ID: (Human) 6427