The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
This intronless gene encodes a transcription factor that is a member of the high mobility group (HMG)-box family of DNA-binding proteins. This protein is the testis-determining factor (TDF), which initiates male sex determination. Mutations in this gene give rise to XY females with gonadal dysgenesis (Swyer syndrome); translocation of part of the Y chromosome containing this gene to the X chromosome causes XX male syndrome.
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Protein Aliases: essential protein for sex determination in human males; HMG box transcription factor Sry1; HMG box transcription factor Sry3BI; sex determining region of Chr Y; sex determining region on Y; sex determining region Y protein; sex-determining region on Y; Sex-determining region Y protein; Testis determining locus; testis determining-Y; Testis-determining factor; testis-determining factor on Y
Gene Aliases: SRXX1; SRXY1; SRY; Sry1; Sry3BI; SRYGENE; TDF; TDY