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Proteintech
SS18 Polyclonal Antibody
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Product Details
22185-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SS18 fusion protein Ag16743
Conjugate
Form
Liquid
Concentration
0.7 mg/mL
Amount
105 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: SHNMPSDGMV GGGPPAPHMQ NQMNGQMPGP NHMPMQGPGP NQLNMTNSSM NMPSSSHGSM GGYNHSVPSS QSMPVQNQMT MSQGQPMGNY GPRPNMSMQP NQGPMMHQQP PSQQYNMPQG GGQHYQGQQP PMGMMGQVNQ GNHMMGQRQI PPYRPPQQGP PQQYSGQEDY YGDQYSHGGQ G
Target Information
The transcriptional coactivator SYT (synovial translocation protein) contains a conserved amino terminal SNH domain and a carboxy terminal QPGY domain, which is a functioning transcriptional activating sequence. Synovial sarcoma translocation (SSX) proteins, including SSX1-5, are transcriptional repressors that contain a repressor domain in their carboxy termini. SSX proteins are localized to the nucleus and expressed in testis and several types of cancers and, therefore, they are classified as C/T (cancer/testis) antigens. The t(x;18) translocation results in the fusion of the amino terminus of SYT to the carboxy terminus of either SSX1 or SSX2; both fusions result in the production of transcriptional activators.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MGC116875; Protein SSXT; Protein SYT; SS18; SS18, nBAF chromatin remodeling complex subunit; synovial sarcoma associated SS18-beta; synovial sarcoma associated SS18-delta; synovial sarcoma associated SS18-gamma; Synovial sarcoma translocated to X chromosome protein; synovial sarcoma translocation; synovial sarcoma translocation, chromosome 18; synovial sarcoma, translocated to X chromosome; Synovial sarcoma-associated Ss18-alpha; SYT; SYTins; unnamed protein product
Gene Aliases: D130059H17; SMARCL1; SS18; SSXT; SYT
UniProt ID: (Human) Q15532, (Mouse) Q62280
Entrez Gene ID: (Human) 6760, (Mouse) 268996
microtubule cytoskeleton organization
cell morphogenesis
chromatin remodeling
regulation of transcription from RNA polymerase II promoter
cytoskeleton organization
positive regulation of cell proliferation
response to xenobiotic stimulus
intracellular signal transduction
negative regulation of cell differentiation
positive regulation of transcription from RNA polymerase II promoter
ephrin receptor signaling pathway
neuronal stem cell population maintenance
positive regulation of stem cell population maintenance
transcription, DNA-templated
regulation of transcription, DNA-templated
response to drug
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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